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In addition, broad genetic and genomic tools, including targeted deletions, transgenics, tissue-specific RNA interference (RNAi) [15], mutagenesis screens, and a genome-scale RNAi screen [16], have been combined with rapidly quantifiable phenotypes for the fat content and nutrition intake to study the energy balance and fat metabolism [17]

He had been talking to us the whole time and he just stared at the camera and it was over