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However, repressive chromatin marks and the recruitment of silencing protein complexes were found in the non-expressing hypermethylated RAJI and MEG-01 cell lines, again validating the interrelationship between DNA methylation and histone marks (Karius et al., 2011)

When ROS levels exceed the scavenging capacity of the redox system, under such situations, can repair oxidized and damaged molecules using NADPH as an original electron source

It might be that the effect of MGO on microglial phenotype is an indirect effect through AGE-RAGE signaling

[DOI] [Google Scholar] 26.Kitahara T
