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Living with the unpredictable and exhausting symptoms of Long COVID, ME/CFS, and MCAS requires immense resilience

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One thing to consider is that because ME/CFS is a severely disabling disease, many patients are house or bedbound and are unable to visit the clinics multiple times for follow-up analyses (39), even though these very severe cases are estimated to be around 25% of the ME/CFS cases (11, 39, 587)

The phosphorylation of HSP60 at Tyr227 and Tyr243 enhances chaperone activity, thus supporting cancer cell survival and proliferation through the activation of oncogenic signaling pathways