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Description
Finally, a number of inherited mutations in genes involved in carnitine shuttling and fatty acid oxidation pathways do not systematically result in carnitine depletion (such that carnitine supplementation may not help mitigate the symptoms) but lead to abnormal profiles of acylcarnitine esters in blood (35, 40)
Hudson & Tabet 2003 Cochrane Review: A Cochrane Review of 15 clinical trials (including 13 of those in the meta-analysis above) assessed 1 to 3 g/day ALCAR supplementation versus placebo over 12 to 52 weeks in participants with mild to moderate dementia or cognitive decline
no toxic effects have been reported in relation to intakes of high doses of L-carnitine
The laboratory personnel verbally confirmed that the patient had been aware of the dietary restrictions before each blood draw
