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LCN2 is an iron trafficking protein that acts as a major driver of post-traumatic neuroinflammation, and genetic inactivation of Lcn2 or LCN2 depletion reduced brain damage and improved neurological outcome after TBI 88,89

Thus, P450scc activity serves as a key regulator in the biogenesis of these crucial signaling molecules

In such a way, the entire quantification process is corroborated and benchmarked

Yin, J., Thomas, F., Lang, J
