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Description
MacKenzie ET et al (1976): Cerebral circulation and norepinephrine: relevance of the blood-brain barrier
Cairns et al., 2006)
Due to their site not on the apical surface of the epithelium but rather on the luminal side, targeting folate receptors (FRs) have been shown to be quite more efficient than targeting other receptors in reducing chemotherapeutic toxicities
and site-specific inhibitors (S1QELs) can suppress this O 2 /H 2 O 2 output without affecting basal respiration, demonstrating that the site of generation dictates specific signaling outcomes [24, 72]
