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Glutathione may be beneficial for protecting cells and tissues from damage by heavy metal toxicity and other environmental toxins, breaking them down into less harmful compounds so the body can rid itself of them

However, the therapeutic utility of doxorubicin is undermined by its dose-dependent cardiotoxicity, possibly arising as a result of futile redox cycling, with NADH dehydrogenase within the mitochondria proposed as the most likely site of anthracycline reduction 9,10

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