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To determine whether dysregulated hepatic glutathione homeostasis and TNF can synergistically contribute to hepatocyte death, we performed cell culture studies using both human hepatoma cells and mouse non-transformed hepatocytes

Previously, as aforementioned, kava ceremonies were only performed and attended by men, while now women are also progressively drinking kava in informal rituals [1]

48 The field of intestinal permeability is relatively new and long-term prospective studies have yet to clearly identify the potential hazards of chronic, low-grade levels of intestinal permeability

Acknowledgements This research was supported by the National Key R&D Program of China (2018YFC1313304, 2018YFC1313300), National Natural Science Foundation of China (81930065, 81871951), Natural Science Foundation of Guangdong Province (2019A1515010233, 2018B030306049), Pearl River S&T Nova Program of Guangzhou (201806010002), and CAMS Innovation Fund for Medical Sciences (CIFMS) (2019-I2M-5-036)