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In brain and other nerve tissues, this acetyl group export by acetyl-L-carnitine out of the mitochondria into the cytosol is important in maintaining normal levels of acetyl groups for the production of acetylcholine and other acetylated neurotransmitters that are so crucial for normal brain andnerve function

Modification of cochrane tool to assess risk of bias in randomized trials

One of the best-known mitochondrial diseases is mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) [82]
