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doi: 10.2337/dc13-0229

Despite its advantages, its important to acknowledge GHK-Cus limitations when compared to traditional acne treatments in a research context: Limited Direct Evidence for Active Acne Vulgaris: While it has anti-inflammatory properties, there is currently limited direct clinical evidence specifically demonstrating GHK-Cu as a primary treatment for active acne breakouts (e.g., reducing papules, pustules, or cysts)

It works primarily through two mechanisms to address pigmentation concerns such as dark spots, dullness, and melasma

Increased circulatory half-life of liposomes after conjunction with dextran