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Recommended clinical approach includes: Baseline evaluation : Consider obtaining serum creatinine, eGFR, and urinalysis before initiating either substance

doi: 10.1016/s0014-2999(99)00486-0

10.1016/j.ajhg.2013.07.022 Summary Keywords cobalamin, hydroxocobalamin, cyanocobalamin, vitamin B12, metabolic Citation Elangovan R and Baruteau J (2022) Inherited and acquired vitamin B12 deficiencies: Which administration route to choose for supplementation

Shungu, a researcher not an MD demonstrated that NAC supplementation (1800 mg/day for four weeks) not only reaches the brain but was able to significantly reduce brain free-radical levels, increased GSH levels, and improved symptoms