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Editor information Editors and Affiliations Rights and permissions Copyright information 2023 Springer Nature Switzerland AG About this entry Cite this entry Fernndez-Veledo, S., Marsal-Beltran, A., Ceperuelo-Mallafr, V., Astiarraga, B., Ced, L

In the presence of ATP and coenzyme A, the enzyme acyl-CoA synthetase (thiokinase) catalyzes the conversion of a fatty acid (or FFA) to an active fatty acid or acyl-CoA, which uses one high-energy phosphate with the formation of AMP and PP i (Figure 221)

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Inhibition of microsomal PGE synthase-1 reduces human vascular tone by increasing PGI(2) : a safer alternative to COX-2 inhibition