john appleton glutathione NAD(P)H, a directly operating antioxidant? - Kirsch - 2001 - The FASEB Journal BLM and BRCA1-BARD1 coordinate complementary

In chicken hepatocytes, copper-induced ROS have been shown to activate the NLRP3 inflammasome and promote the expression of caspase-1 protein, subsequently leading to pyroptosis

These excipients play distinct and complementary roles in overcoming anatomical and physiological barriers, ultimately enhancing the therapeutic performance of intranasal formulations (Gnger and Schindowski, 2018)

Here, we show that the small molecule proteostasis regulator AA147 protects against glutamate-induced cell death in a neuronal-derived cell culture model by reducing intracellular levels of reactive oxygen species

Collectively, Kang and colleagues reinforced the observation that cystine starvation could sensitize cancer cells to ferroptosis by inducing intracellular glutamate accumulation, and uncovered that GCLC potentially alleviates cellular ferroptotic stress by both mediating GSH synthesis and scavenging glutamate