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Inflammation-associated Co-morbidity between depression and cardiovascular disease

A 2023 update ( Hallmarks of Aging: An Expanding Universe ) extended the list to twelve

Oxidative Stress The concept of oxidative stress has developed from the free radical theory of oxygen toxicity developed in the 1950s with studies such as those by Rebecca Gerschman showing that oxygen poisoning and X-irradiation can both produce oxygen-derived free radicals [35,36]
