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Tetracyclines, including doxycycline, form a stable calcium complex in bone-forming tissue

Visible fading of dark spots and more even tone typically appears after 24 weeks of consistent daily use

Significant increases in cellular GSH level were detected in cultures grown at 100 g/ml or 150 g/ml 5-FOA, but not at 50 g/ml 5-FOA (Figure S2A)

doi: 10.1038/nature10662
