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Geng et al.(2025) demonstrated in an animal study that inulin ameliorates metabolic disturbances and ovarian dysfunction in PCOS rats by modulating the gut microbiota, likely through mechanisms involving enhanced SCFA production and reduced systemic inflammation (99)

Regulating selective splicing of neurexins We know that neurexins consist of six LNS structural domains (LNS1LNS6) interspersed with three EGF-like repeats, and that there are six special selective splice sites (SS1SS6) under this basic structure [47]

Thus, ferroptosis induction in HSCs by targeting the system Xc-/GPX4 axis might be an effective approach to ameliorate liver fibrosis

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