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Continued research into the immunological aspects of ammonia metabolism in the TME is essential for advancing tumor immunotherapy targeting ammonia death, with the goal of achieving innovative breakthroughs in cancer treatment and providing clinical benefits to cancer individuals

In this context, HIV-1 intron-containing RNA (icRNA)the unspliced, intron-retaining transcript that is Rev/RRE-dependent and exported via CRM1is detectable in previously infected CD4 T cells, macrophages, and microglia

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