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We further observe that once heme moves inside the cavity toward the defined binding pocket, its interactions with R77 C , R81 C and R136 C become stronger while its interactions with the surface lysine groups diminish

The GSH/GSSG ratio is a commonly used sensitive early biomarker of the redox homeostasis

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[DOI] [PMC free article] [PubMed] [Google Scholar] 5.Anand U, Bandyopadhyay A, Jha NK, Prez de la Lastra JM, Dey A: Translational aspect in peptide drug discovery and development: An emerging therapeutic candidate
