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Description
Erratic timing dosing at 9am one week and 6pm the next prevents this adaptation and can increase dropout risk
Notably, there is no direct interaction between the two LepR ECDs, suggesting that receptor dimerization is primarily ligand-dependent, as has been observed for other class 1 cytokine receptors 26
10.1053/j.ajkd.2014.09.023 26 HuD
A key issue identified across the reviewed studies is the variability in the composition and lack of standardization of LBP extracts used
