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doi: 10.1111/bph.12746 41 CoolesP.MichaudR
It has been more than three decades since this classification was introduced
doi: 10.1053/j.gastro.2006.11.023
Building on these findings, studies have shown that the active mitochondrial network in CRC cells exerts a physical metabolic occupancy effect that impedes immunological synapse formation, while the associated release of ROS further suppresses immune cell function
