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Description
The microbiota-gut-bone axis and bone health

During tumor immunotherapy, IFN- released by activated CD8 + T cells also upregulates the expression of ACSL4 in tumor cells through the STAT1-IRF1 signaling pathway [111]

In turn, damaged podocytes lose their ability to maintain glomerular structure and trigger a local inflammatory reaction

5H, I), while overexpression of a codon-optimized L2HGDH (L2HGDH OPT ), which is resistant to the designed sgRNA, reverses this effect (Fig
