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Inhibition of PGC-1 expression has been shown to result in decreased expression of the mitochondrial fusion protein Mfn2, increased expression of p-Drp1, and increased mitochondrial fragmentation (Guo et al., 2015)

The analysis of fissure numbers in brain tissue across different experimental groups offers valuable insights into the structural effects of various treatments on insomnia-induced changes

DSIP has been studied for decades, but the evidence remains limited, mixed, and not strong enough to treat it as a proven solution for insomnia or sleep disorders

Impaired barrier function does not simply and directly lead to disease in animal models of disease