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SARS-CoV-2 ORF6 protein has also been shown to dysregulate redox homeostasis by decreasing Nrf2 expression, which can enhance viral replication 69
It should be noted that previous comparisons of his-tagged and untagged GSTs have not detected any significant differences caused by the tag in the catalytic properties of the enzymes
Nature 432 , 396401 (2004)
