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Description
ACP1 has cytosolic location, whereas ACP2 and ACP5 are lysosomal enzymes

Overall, although the [ 11 C]Ro15-4513 V T reflects the net effect of the availability of these different GABA-A receptors, the 20-fold greater affinity of [ 11 C]Ro15-4513 for 5-GABA A Rs and the enriched expression of 5-GABA A Rs in the hippocampus indicates the lower [ 11 C]Ro15-4513 hippocampal availability is likely to predominantly reflect lower 5-GABA A R levels
Vukojevic, J., et al., Pentadecapeptide BPC 157 and the central nervous system
A 34-min linear gradient (375% acetonitrile in 0.1% formic acid), at a flow rate of 350 nL/min, was used to separate peptides on polaris-HR-Chip C18 column (150 mm long 75 m inner diameter)
