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Intriguingly, Met4 is kept in a transcriptionally inactive state by the post-translational poly-ubiquitin modification at lysine residue 163 [16]

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There are three main isoforms of SOD, characterized by their cellular localization: cytosolic (SOD1 (CuZn-SOD)), mitochondrial (SOD2 (Mn-SOD)), and extracellular (SOD3 (EC-CuZn-SOD))
