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Description
Drosophila melanogaster glutamate-cysteine ligase activity is regulated by a modifier subunit with a mechanism of action similar to that of the mammalian form

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However, these protective effects were attenuated when either LY294002 (a specific inhibitor of the PI3K/Akt/mTOR pathway) or anisomycin (an activator of the TLR4/p38/MAPK pathway) was administered

2019 Jul;117:170089
