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Description
In order to get rid of contaminating metal ions in the buffer, the mobile phase was eluted through the Chelex100 Chelating Ion Exchange resin (Sigma, Merck KGaA, Darmstadt, Germany) prior to liquid chromatographic separation
2020;318(4):H883-H894

The main mechanism of action of chemical enhancers is based on the disruption of the lipid layer of the stratum corneum and the interaction with lipids, proteins, and keratinocytes [87]

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