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This compound enables detailed investigation of melanogenesis, neuroendocrine signaling, appetite regulation, and metabolic pathways within a single, structurally defined framework

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External validation data from the Popular Diets Study To assess the results of our primary analysis and identify diet-responsive metabolites, we utilized metabolomic data from the Popular Diets Study, an earlier randomized crossover feeding trial 16 , as an external validation study to ensure the robustness of our findings

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3g and Supplementary Fig

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