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The aforementioned findings could suggest that modifications to the gut microbiota during gestation play a role in developing pregnancy-specific metabolic alterations, including elevated levels of inflammatory markers and energy content

ROS are then transformed into less reactive products by antioxidative enzymes, while phase II conjugating enzymes, such as glutathione S-transferases (GSTs), participate in detoxification of their reactive secondary products [17]

Moreover, the identification of ferroptosis markers is crucial in differentiating them from cell death induced by oxidative stress and in guiding the development and evaluation of ferroptosis-specific drugs

Moen MD, Keating GM, Vogel VG