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Targeting the human double minute (HM)-2 p53 ubiquitin ligase as a strategy against non-Hodgkin lymphoma
(6) People with cirrhosis have a 1 to 4 percent annual risk of developing liver cancer and a 3 to 6 percent risk of hepatic decompensation (the development of serious, life-threatening liver-related problems)

Fredrickson DS, Lux SE, Herbert PN
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Prog Appl Microbiol