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and Vilardell, J., "Regulated pre-mRNA splicing: the ghostwriter of the eukaryotic genome", Biochem

Recommendations were developed from a literature review, practitioner management survey, and nominal group process involving two face-to-face meetings

10.1097/00005344-199322008-00043 21 FalcettiE.HallS

For instance, drug exposure drives the phenotypic alterations of tumor cells, including dedifferentiation, EMT or trans-differentiation, marked by upregulated EMT-related transcriptional factors (TFs), including Zinc finger E-box binding homeobox 1 (ZEB1), ZEB2 and SLUG, that suppress pro-apoptotic proteins (BIM, BMF) and activate anti-apoptotic proteins (Bcl-xL, BCL- 2, MCL1) [38,39,40]