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Compounding pharmacies in Canada are regulated on both the federal and provincial levels

Foundational work should include translational trials that pair GLP-1RA therapy with deep immunophenotyping (Th1/Th17/Treg balance, inflammasome activity), adipokine profiling (leptin, adiponectin), and gut-barrier/microbiome readouts, alongside thyroid-specific endpoints (Thyroid Peroxidase Antibodies (TPOAb)/Thyroglobulin Antibodies (TgAb)/TRAb trajectories, ultrasound echogenicity and volume, Doppler vascularity, and patient-reported outcomes) [1,3,9,22]

[DOI] [PubMed] [Google Scholar] Wu C, Wu G, Wang Z, Zhang Z, Qian Y, Ju L

doi: 10.1111/acel.12927
