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Description
Phase IIa, placebo-controlled, randomised study of lutikizumab, an anti-interleukin-1 and anti-interleukin-1 dual variable domain immunoglobulin, in patients with erosive hand osteoarthritis
Professional administration is non-negotiable to ensure correct dosage, proper technique, and immediate response to any reactions

Lutein directly reduces the activation of NF-B and inhibits the levels of mRNA and protein of TNF-, IL-1, and COX-2
PMID 1691208.
