alcohol acetaminophen syndrome glutathione Ethanol Metabolism and Its Impact on Health Downregulation of Glutathione-Mediated Detoxification Capacity

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Animal experiments confirmed that dural injection of bone marrow mesenchymal stem cell-derived exosomes miR-367-3p significantly reduced the expression of EZH2 in spinal cord tissues of EAE mice, increased the expression of SLC7A11, GPX4, GSH, and SOD, decreased the levels of Fe 2+ and MDA, inhibited spinal cord iron deposition, ferroptosis, and inflammation, and alleviated spinal cord injury (Fan et al., 2023)

Arch Biochem Biophys 408:16, PMID: 12485597 Hogg N (2002) The biochemistry and physiology of S -nitrosothiols

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