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Description
Our novel NNMT inhibitors display excellent physical chemical properties (e.g., membrane permeability), selectivity, and cellular inhibitory activity against NNMT, concomitantly enhancing the levels of the cofactors SAM and NAD + that independently regulate cellular energy metabolism and epigenetic modifications
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Where the peptide enters the body determines where it concentrates, how much reaches systemic circulation, and which tissues it can reach at therapeutic levels
