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In the clonal selection mechanism, it was found that a subpopulation of cells with drug-tolerance/resistance can be detected in patient cancer tissues prior to treatments
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Importantly, its therapeutic efficacy is amplified when coadministered with borneol, which enhances kaempferol's blood brain barrier permeability and central nervous system bioavailability (Zhang et al
Androgen-regulated expression of arginase 1, arginase 2 and interleukin-8 in human prostate cancer
