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By damaging IL-17 cytokines, AIRE gene mutations are thought to impair the IL-17 pathway's function, resulting in CMC in people with APECED
The Obesity Paradox and Mortality in Older Adults: A Systematic Review
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This response appears to be attenuated by L-carnitine supplementation which reduces intracellular hypoxanthine and xanthine oxidase following resistance exercise bouts [109] whereas other experimental investigations failed to demonstrate such effect [116, 117]
