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Description
Treatment of 24-month-old mice (equivalent to elderly humans) with NNMT inhibitors rescued age-related deficits in muscle stem cell activity
J Clin Invest 1971;50:10004
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MuSC Proliferation In aged skeletal muscle, NNMT overexpression is linked to impaired NAD+ salvage, dysregulated SIRT1 activity, and increased muscle stem cell (MuSC) senescence
