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Ranjekar PK, Hinge A, Hegde MV, Ghate M, Kale A, et al

For a 5 mg Tb-500 vial with 2 mL bacteriostatic water, the 2.5 mg per mL concentration means 0.1 mL (10 units) delivers 0.25 mg or 1 mL delivers 2.5 mg

These alterations cause elevated intracellular levels of Na and Ca, disrupt ionic homeostasis, and result in cell swelling [103]

Thus, our knowledge of the mechanisms that govern the downregulation of GPCRs is still expanding, and it is possible that other receptors may have additional atypical post-endocytic itineraries that are yet to be elucidated