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Gastrointestinal changes after bariatric surgery

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In addition, there are other neuropathological mechanisms induced by L-Glu, including excitotoxicity, in which L-Glu overactivates its receptors, including those for N-methyl-D-aspartate (NMDA), -amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA), kainate acid (KA), and metabotropic glutamate (mGlu), resulting in an excessive influx of calcium ions (Ca 2+ ) into neurons, leading to the generation of reactive radicals and increased levels of proapoptotic proteins [29,30,31,32]