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For everyone else, its a stress test of what we mean when we call a peptide long-acting. What Pfizer announced (and why it matters) Pfizers announcement is straightforward on paper: berobenatide is an investigational GLP-1 receptor agonist peptide designed to support a monthly maintenance regimen, delivered in a low 0.5 mL injection volume
A study led by Cho et al
In addition, TET2 deficiency in murine macrophages increases JNK1 activation-mediated NLRP3 inflammasome activation and BRCC3-mediated NLRP3 deubiquitylation (224)
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