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Potential concerns and unknowns Several important unknowns remain regarding 5-amino-1mq safety

Expanded obesity drug coverage can increase Medicaid spending and put pressure on overall state budgets, and states are now facing tighter budget conditions and longer-term fiscal uncertainty, due in part to the federal Medicaid cuts in the 2025 reconciliation law, causing state Medicaid programs to re-evaluate their obesity drug coverage

Remember though that the restriction is about the delivery by injection

However, for patients without a true vitamin B12 deficiency, research shows that B12 injections are unlikely to boost energy or reduce fatigue