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In addition to PHGDH, serine hydroxymethyltransferase (SHMT) is also implicated in tumorigenesis

Commandeur JNM, Stijntjes GJ, Vermeulen NPE (1995) Enzymes formation and transport and systems involved in the of glutathione
Thereafter, medium was replaced every 23 days without disturbing the cells and the culture dish was placed in the same location in the microscope to be able to follow the same field of view

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