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Moreover, various specialized pro-resolving mediators (SPMs) produced from omega-3 PUFAs help in moderating undue neuroinflammatory responses and inflammatory pain, facilitating communication between glial cells and neurons
Walker AW, Duncan SH, Louis P, Flint HJ

Among the agents that mediate their effects through S -glutathionylation, NOV-002 has been most extensively studied, with a phase III trial (NCT00347412) completed in advanced NSCLC [104], and data available from phase II trials in breast and ovarian cancers [105]
