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The experimental evidence generated in a relevant experimental TD model suggests key molecular mechanisms in the striatum to guide future development of preventive and palliative antidyskinetic strategies
Crystals of wild-type mIDH2 were obtained at 4 C with a reservoir solution consisting of 0.1 M sodium citrate tribasic dehydrate (pH 5.6), 11.5% (v/v) 2-propanol and 10.8% (w/v) PEG 4000
ACh exerts tonic effects to maintain constriction of the lower esophageal sphincter, with ACh signaling compromised in a rat model of gastrointestinal reflux disease (210)
