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Collectively, these findings indicate that SIRT1 is essential for the maintenance of redox balance and mitochondrial function in the cochlea after traumatic noise exposure, thus providing a promising therapeutic target for NIHL treatment
doi: 10.1016/S0140-6736(11)61452-9 51 DuntasLH
For natural compounds like rhamnetin, it is vital to establish a comprehensive understanding of its toxicological profile, including its effects across different dosing regimens, routes of administration, and target populations
A double-edged sword with a therapeutic target: Iron and ferroptosis in immune regulation
