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hypoxia, wound fragments misadaptation, infection) tend to hamper this process resulting in scar formation or delayed healing, and probably induce VEGF formation by more than one mechanism (22)
An MRI can also show bleeding at the site of a ruptured plaque
Crucially, DM-associated metabolic dysregulation extends beyond biosynthetic disruption to critically impair surfactants antimicrobial functionality

Mulholland et al., 1991
