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Psychological stress is widely recognized as a major contributor to premature hair graying (PHG), supported by numerous studies in both humans and animal models

doi: 10.1155/2019/7286737

However, the potential for isothiocyanates to inhibit various isoforms of the cytochrome P450 (CYP) family of enzymes raises the potential for interactions with drugs that are CYP substrates (see Biological Activities)
