l carnitin hashimoto Hashimoto's Thyroiditis and the Keto Diet Carnitine and Thyroid Disease -
Description
PLoS One 17:e0271307
Brain Behav
The depletion of acetylcholine not only causes devastating cognitive brain fog but also contributes to the rapid heart rate, digestive motility issues, and temperature dysregulation that make dysautonomia so debilitating
For instance, a high acetyl-CoA/CoA ratio in the mitochondrial matrix inhibits pyruvate dehydrogenase (PDH) that catalyzes the oxidative decarboxylation of pyruvate to acetyl-CoA (Pietrocola et al., 2015)
