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Although exact mechanisms are still unclear, CBD may inhibit endocannabinoid signaling and its effects on synaptic plasticity through negative allosteric modulation [83], while the enhancement of vasopressin and oxytocin release by CBD and other epigenetic modulations have also been proposed [78,84]

And oxidative stress is when your body has an imbalance between the free radicals in it and the ability to fight off those free radicals

3.5.3 Doxorubicin-induced renal intoxication Doxorubicin (DOX), a chemotherapeutic agent classified as an anthracycline, is a highly effective therapeutic used in the management of various hematological cancers and solid tumors (Tangpong et al., 2011)

Formulation matters too